Ormond disease - idiopathic retroperitoneal fibrosis

Ormond's disease (idiopathic retroperitoneal fibrosis, retroperitoneal fibrosis) is the progressive compression of one (more often both) ureter with a scar (fibrous) tissue. Often there is a complete closure of their lumen.
To date, reliable causes of this disease are not fully understood

Possible causes of Ormond's disease
- Development on the basis of inflammatory diseases of female genital organs
- Cholangitis and cholecystitis
- Ileit
- Pancreatitis
- Lymphangitis
- Granulomatous vasculitis
- Hematoma formed in the retroperitoneal space due to trauma
In addition, the researchers put forward an immunoallergic hypothesis of the appearance in the tissues of retroperitoneal fibrotic changes

Symptoms

- Attack stupid pain in the lumbar region
- Pain in the lower abdomen and in the testicles
- Reduced appetite and fatigue
- Increased blood pressure
- Increased ESR
и нефрогенной гипертонии As the progression of Ormond's disease may occur complications in the form of renal failure and nephrogenic hypertension

Diagnostics

The diagnosis is based on the results of excretory urography and a survey image of the upper urinary tract. To help retrograde ureteropyelography, to determine the state of the upper urinary tract resorted in the event that there is a sharp decline in kidney function. Also, to assess the anatomical and functional state of the kidneys, radioisotope methods of investigation (scintigraphy and isotope renography) are used, and ultrasound examination of the kidneys is used to establish an accurate picture of hydronephrosis transformation

Treatment

Treatment directly depends on the prevalence and localization of the disease, the presence of urinary infection and the degree of violation of the passage of urine. In most cases, patients are assigned surgical treatment.
In the postoperative period, corticosteroids (cortisol daily for 25 mg for two to three months) are applied for a long time to suppress the development of fibrous tissue. Parallel to this, other types of resorptive therapy (aloe, lidase)

Forecast

If there is no proper treatment for Ormond's disease, the prognosis is unfavorable, because of the progression of chronic renal failure and due to the increase in hydronephrosis transformation, a lethal outcome is possible. After the operative treatment the prognosis is more favorable, however, relapse of the disease is possible.