Allerfex: instructions for use

Please note that before buying the drug Allerfex, you should carefully read the instructions for use, methods of application and dosage, as well as other useful information on the drug Allerfex. On the site "Encyclopaedia of Diseases" you will find all the necessary information: instructions for use, dosage, contraindications, as well as reviews of patients who have already used this medication.

Pharmacological group


Nosological classification (ICD-10)

J30 Vasomotor and allergic rhinitis

J30.1 Allergic rhinitis caused by pollen of plants

L50 Urticaria

T78.3 Angioedema

Allergy - Composition and form of release

The tablets covered with a cover.

1 tab. fexofenadine hydrochloride: 30 mg; 120 mg; 180m.

Excipients: MCC; calcium phosphate disubstituted; potato starch; impellosis (croscarmellose sodium); magnesium stearate; talc; silicon dioxide colloid (aerosil); PVP low molecular weight medical (povidone)

The composition of the shell: Opadry II (polyvinyl alcohol, partially hydrolysed, talc, titanium dioxide, polyethylene glycol 3350, lecithin (soy), aluminum carbamide-based lacquer, aluminum lacquer based on ponso 4R, aluminum lacquer based on indigo carmine)

In the contour acheikova packing 10 pcs .; in a pack of cardboard 1, 2 or 3 packs; or in banks of light-protective glass or polymeric banks, or in polymer bottles of 10, 20 and 30 pcs .; in a pack of cardboard 1 jar or a bottle.

Allergies - Pharmacological action

Allergy is an antihistamine, a pharmacologically active metabolite of terfenadine, which stabilizes the membranes of mast cells, reduces the release of histamine and other biologically active substances from them.

The antihistamine effect manifests itself 1 hour after ingestion, reaches a maximum after 6 hours and lasts for 24 hours. After 28 days of admission, there was no addiction. In the dose range of 10-130 mg, a dose-dependent effect is noted. Does not cause significant changes in the QT interval, does not have a sedative effect.


After oral administration, it is rapidly absorbed from the digestive tract, Cmax is determined after 1-3 hours. The mean Cmax after taking 180 mg is approximately 494 ng / ml, and after taking 120 mg 427 ng / ml. Binding to plasma proteins is 60-70%. T1 / 2 after repeated intake of 14.4 hours. It penetrates into breast milk. It is subject to partial (5% of the dose) extrahepatic metabolism. It is excreted mainly with bile (80%), 11% with kidneys in unchanged form.

Allergy - Indications for use

Seasonal allergic rhinitis ;

Chronic urticaria .

Allergies - Contraindications

Hypersensitivity; pregnancy ; lactation period; children's age (up to 6 years).

With caution: chronic renal failure; hepatic insufficiency .

Fexofenadine is contraindicated in pregnancy and lactation (breastfeeding).

Fexofenadine penetrates into breast milk. If fexofenadine is needed during lactation, the question of stopping breastfeeding should be addressed.

Allergy - Side effects

Headache, drowsiness, nausea, dizziness .

Rarely (less than 1 case per 1000 prescriptions): a feeling of fatigue, insomnia, nervousness, sleep disturbance.

In some cases: skin rash, hives, itching , other hypersensitivity reactions (angioedema), shortness of breath.

Interaction with other drugs

When co-administered with erythromycin or ketoconazole, the concentration of fexofenadine in plasma increases 2-3 times.

Reception of aluminum-or magnesium-containing antacids 15 minutes before fexofenadine intake leads to a decrease in bioavailability of the latter (the time interval between their intake should be at least 2 hours).

Does not interact with omeprazole, with drugs metabolized in the liver.

Allergy - Method of administration and dose

Dosing and Administration Inside, adults and children from 12 years and older to 120 mg / day once, with chronic urticaria 180 mg / day once.

Children 6-11 years old with allergic rhinitis and hay fever 30 mg twice a day;

patients with renal insufficiency 30 mg once.

special instructions

It is possible to perform works that require a high concentration of attention and speed of psychomotor reactions (except for patients who have an unconventional reaction to drugs). Thus, before you begin to perform these works (driving vehicles, controlling the mechanisms), you must first check the individual reaction to the drug.

Use with caution in patients with renal insufficiency.

Use with caution in patients with hepatic insufficiency.

Use with caution in elderly patients.

Administration of the drug to children under 6 years is not recommended.

Analogues Allerfeek : Gifast, Dinox, Rapido, Telfast, Fexadin, Fexo, Fexofast.

Storage conditions and shelf life of the preparation

In a dry, the dark place at a temperature of no higher than 25 ° C.

Shelf life 2 years.

We want to pay special attention to the fact that the description of the drug Allerfex is for informational purposes only! For more accurate and detailed information about the drug Allerfex, please refer exclusively to the manufacturer's annotation! Do not self-medicate! You should definitely consult a doctor before starting the drug!